Who we are

Ultrasonic 3d Printing: We seek to enhance the translation of tissue regeneration research to the clinic across organ systems by providing an acoustic holography technology to print tissue patches directly inside the human body. In addition to being less invasive, EndoGen hypothesizes that there are inherent benefits of directly printing a tissue patch in vivo rather than transplanting a patch cultured in vitro. Endogen’s proposed use of sound for assembling the tissue (as opposed to deposition / light-based) offers better scaling in a dynamic physiological environment and access to sites deeper in the body. While this clinical tool will redefine what is surgically possible, it will take a significant effort with corresponding risk, cost, and time to develop. The first step in de-risking the technology is the design and fabrication of a benchtop ultrasonic 3d bioprinter for testing of bioinks. This device will allow labs to evaluate whether acoustic holographic assembly of bioink particles is compatible with their tissue engineering formulations, making in vivo 3d bioprinting a worthwhile, realizable technology. 

Pediatric Devices: Pediatric surgeons often create bench side tool solutions to address the lack of suitable surgical instruments for their patients; however, these tool ideas often do not make it beyond the surgeon’s operating room due to the cost and regulatory hurdles of productization. Our goal is to identify an efficient, sustainable pathway for producing simple Class I surgical instruments by designing them to be 3d printed using previously approved FDA materials. Eventually, we aim to offer a digital repository of various tool designs that would enable hospitals to 3D print Class I surgical tools on-premise, reducing reliance on and associated costs with traditional mass manufacturing and thereby improving the efficiency with which surgeons' simple surgical tool ideas are translated to approved, widely accessible products.